Overview
1
Your Name: Prodrugs are an area of medicinal chemistry that has been extensively researched over the last several years. Prodrugs are designed to be initially inactive until further activated into the active form of the drug (which could include also esterification or trans-esterification event). For example: Aspirin is a prodrug that gets converted to salicylic acid. (a) Draw a complete arrow-pushing mechanism showing how aspirin is converted into salicylic acid (say by the stomach acylating enzyme at low pH). A scheme of the overall transformation is shown below. In your peer reviews, comment on any step that needs to be corrected.